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Heme uptake by Leishmania amazonensis is mediated by the transmembrane protein LHR1.

Trypanosomatid protozoan parasites lack a functional heme biosynthetic pathway, so must acquire heme from the environment to survive. However, the molecular pathway responsible for heme acquisition by these organisms is unknown. Here we show that L. amazonensis LHR1, a homolog of the C. elegans plas...

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Detalles Bibliográficos
Principais autores: Chau Huynh, Xiaojing Yuan, Danilo C Miguel, Rebecca L Renberg, Olga Protchenko, Caroline C Philpott, Iqbal Hamza, Norma W Andrews
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22807677/pdf/?tool=EBI
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