ER stress sensor PERK drives ferroptosis by disrupting MAMs-mediated mitochondrial homeostasis and promoting mtROS accumulation in acute myocardial infarction

Acute myocardial infarction (AMI) is a life-threatening condition in which ferroptosis represents an important form of regulated cardiomyocyte death, yet its upstream regulatory mechanisms remain incompletely understood. In this study, we investigated the role of the endoplasmic reticulum (ER) stres...

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Váldodahkkit:	Xueshu Tao, Yunxiang Zhang, Jiao Pang, Zihan Liao, Gaohan Chen, Xue Zhong, Xingrui Cao, Ying Lin, Dawei Guan, Yuan Tian, Liang Hao, Rui Zhao, Zhipeng Cao
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2025-12-01
Ráidu:	Pharmacological Research
Fáttát:	PERK Acute myocardial infarction MAMs Ferroptosis Mitochondrial dysfunction mtROS
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S1043661825004542
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