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Sinomenine Protects against Early Brain Injury by Inhibiting Microglial Inflammatory Response via Nrf2-Dependent Pathway after Subarachnoid Hemorrhage

Microglial activation and sustained inflammation plays an important role in the processes of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Sinomenine (SIN) has been demonstrated to have neuroprotective effects in the traumatic brain injury (TBI) model. However, the role of SIN in SAH...

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Principais autores: Chuanjing Fu, Heng Xin, Zhengting Qian, Xiang Li, Juemin Gao, Youwu Fan, Yong Tang, Yan Shi, Ding Li, Heming Wu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-04-01
Serier:Brain Sciences
Fag:
sinomenine
microglia
subarachnoid hemorrhage
apoptosis
Online adgang:https://www.mdpi.com/2076-3425/13/5/716
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