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The role of the NMD factor UPF3B in olfactory sensory neurons

The UPF3B-dependent branch of the nonsense-mediated RNA decay (NMD) pathway is critical for human cognition. Here, we examined the role of UPF3B in the olfactory system. Single-cell RNA-sequencing (scRNA-seq) analysis demonstrated considerable heterogeneity of olfactory sensory neuron (OSN) cell pop...

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Hoofdauteurs: Kun Tan, Samantha H Jones, Blue B Lake, Jennifer N Chousal, Eleen Y Shum, Lingjuan Zhang, Song Chen, Abhishek Sohni, Shivam Pandya, Richard L Gallo, Kun Zhang, Heidi Cook-Andersen, Miles F Wilkinson
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2020-08-01
Reeks:eLife
Onderwerpen:
NMD
Upf3b
olfactory sensory neuron
scRNA-seq
olfactory receptor
anti-microbial genes
Online toegang:https://elifesciences.org/articles/57525
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