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Design, synthesis and H1-antihistaminic activity of novel 1-substituted-4-(3-chlorophenyl)-[1,2,4] triazolo [4,3-a] quinazolin-5(4H)-ones

In the present study a series of 1-substituted-4-(3-chlorophenyl)-[1,2,4] triazolo [4,3-a] quinazolin-5(4H)-ones were synthesized and screened for their H1-antihistaminic activity. The synthesized compounds were characterized by IR, 1H-NMR, mass spectral data and purity of the compounds was determin...

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Autores principales: Manavalan Gobinath, Natesan Subramanian, Veerachamy Alagarsamy
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer 2015-05-01
Colección:Journal of Saudi Chemical Society
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S1319610312000361
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