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Metabolic Alterations in Cancer Cells and the Emerging Role of Oncometabolites as Drivers of Neoplastic Change

The mitochondrion is an important organelle and provides energy for a plethora of intracellular reactions. Metabolic dysregulation has dire consequences for the cell, and alteration in metabolism has been identified in multiple disease states—cancer being one. Otto Warburg demonstrated that cancer c...

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Principais autores: Zhengqiu Zhou, Elochukwu Ibekwe, Yevgen Chornenkyy
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-01-01
Serier:Antioxidants
Fag:
mitochondria
oncometabolites
cancer
metabolic re-programming
aerobic glycolysis
mitochondrial dynamics
Online adgang:http://www.mdpi.com/2076-3921/7/1/16
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