Lung adenocarcinoma with EGFR exon 19 insertion identified using a compact panel and its response to osimertinib: a case report

An 80-year-old man underwent a left lower lobectomy for lung adenocarcinoma. Next-generation sequencing in a clinical trial identified an epidermal growth factor receptor (EGFR) exon 19 insertion (exon19ins), which was not detected by the Oncomine™ Dx Target Test®, a companion diagnostic tool for EG...

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Principais autores:	Mika Horie, Kazuhisa Nakashima, Kojiro Hata, Yoshihiro Amano, Mika Nakao, Tamio Okimoto, Yukari Tsubata, Takeshi Isobe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
coleção:	Respiratory Medicine Case Reports
Assuntos:	EGFR uncommon mutation EGFR exon 19 insertion Lung cancer Lung cancer compact panel dx Osimertinib
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213007125001753
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