Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

Abstract Photodynamic therapy (PDT) holds promise for tumor ablation, but the clinical translation of photosensitizers, such as chlorin e6 (Ce6), is limited by poor aqueous solubility, low bioavailability, and insufficient tumor selectivity. To address these limitations, we constructed a nanobody–ph...

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Auteurs principaux:	Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2026-06-01
Collection:	View
Sujets:	nanobody Nectin‐4 photodynamic therapy photosensitizer tumor targeting
Accès en ligne:	https://doi.org/10.1002/VIW.20250185
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