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Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties

Abstract Background Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by 5′-adenosine monophosphate-activated protein kinase (AMPK), a master energy sensor of the cell. Clinically, treatment with Z...

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Auteurs principaux: Amber F. MacDonald, Ahmed Bettaieb, Dallas R. Donohoe, Dina S. Alani, Anna Han, Yi Zhao, Jay Whelan
Format: Artigo
Langue:Inglês
Publié: BMC 2018-06-01
Collection:BMC Complementary and Alternative Medicine
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Accès en ligne:http://link.springer.com/article/10.1186/s12906-018-2255-0
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