Rapid screening and identification of influenza virus polymerase inhibitors from Rubus idaeus L. by at-line nanofractionation

The N-terminal region of the polymerase subunit (PAN) is considered as the most promising target for the development of broad-spectrum antivirals, since it is highly conserved in structure and sequences among different influenza strains. In this study, a PAN based at-line nanofractionation (ANF) pla...

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Detalhes bibliográficos

Principais autores:	Zhixu Chen, Rongkai Gu, Mingming Zhao, Kefeng Linghu, Huanwei Fan, Tingting Zhang, Jincai Wang, Zhengjin Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-11-01
coleção:	Journal of Chromatography Open
Assuntos:	N-terminal region of the polymerase subunit Influenza Rubus idaeus L. High-throughput screening
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2772391725000763
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