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Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction.

Controlled inflammatory responses of myeloid cells recruited to wounds are essential for effective repair. In diabetes, the inflammatory response is prolonged and augmented over time, with increased myeloid cells present in the wound that fail to switch from a pro-inflammatory phenotype to a pro-hea...

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Detalhes bibliográficos
Principais autores: Salma Alrdahe, Hadeel Al Sadoun, Tanja Torbica, Edward A McKenzie, Frank L Bowling, Andrew J M Boulton, Kimberly A Mace
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2019-01-01
coleção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0223980
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