Evidence for a purifying selection acting on the β-lactamase locus in epidemic clones of methicillin-resistant <it>Staphylococcus aureus</it>

<p>Abstract</p> <p>Background</p> <p>The β-lactamase (<it>bla</it>) locus, which confers resistance to penicillins only, may control the transcription of <it>mecA</it>, the central element of methicillin resistance, which is embedded in a polymorphic heterelogous chromosomal cassette (the SCC<it>mec...

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Principais autores:	de Lencastre Hermínia, Krippahl Ludwig, Portelinha Ana, Milheiriço Catarina, Oliveira Duarte C
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2011-04-01
Series:	BMC Microbiology
Assuntos:	β-lactamase β-lactam resistance allelic variation MSSA MRSA <it>mecA </it>stabilization
Acceso en liña:	http://www.biomedcentral.com/1471-2180/11/76
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