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Safety and immunogenicity of inactivated Zika virus vaccine by gamma irradiation

Developing the Zika virus (ZIKV) vaccine remains a critical global public health need. This study assessed the safety and immunogenicity of gamma-irradiated Thai ZIKV isolate. Inactivation was confirmed by serial passaging and detection of viral replication using RT-PCR, which demonstrated complete...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Pumin Sintara, Puttawat Suphaprueksapong, Suwimol Jetawattana, Witthawat Wiriyarat, Yada Akkhawattanangkul, Komgrid Charngkaew, Nusara Chomanee, Jantip Saelee, Artit Wongsa, Thongkoon Priengprom, Boonrat Tassaneetrithep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-10-01
Schriftenreihe:Vaccine: X
Schlagworte:
Gamma irradiation
Inactivation
Inactivated vaccine
Zika virus
Animal
Vaccine safety
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2590136225001007
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