Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.
The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of cytotoxicity is not well understood. We investigated the...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2010-09-01
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| coleção: | PLoS ONE |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20927383/?tool=EBI |
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