The IL-33/ST2 Axis Protects the Hippocampus from LPS-Induced Inflammation and Damage by Modulating Microglial Phenotype

<b>Background/Objectives:</b> Systemic inflammation is a known driver of neurodegenerative processes, with amyloid accumulation and neuronal loss. The Interleukin-33 (IL-33)/Suppression of Tumorigenicity 2 (ST2) signaling pathway has emerged as a critical immune regulator with dual roles in maintain...

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Detalhes bibliográficos

Principais autores:	Jelena Nedeljkovic, Jelena Milovanovic, Vladimir Markovic, Natalia Solovjova, Sara Mijailovic, Nebojsa Zdravkovic, Nikola Nedeljkovic, Marija Milovanovic
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-02-01
coleção:	Biomedicines
Assuntos:	IL-33 ST2 microglia neuroinflammation LPS neurodegeneration
Acesso em linha:	https://www.mdpi.com/2227-9059/14/2/459
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