Transcriptome meta-analysis and validation to discovery of hub genes and pathways in focal and segmental glomerulosclerosis

Abstract Background Focal segmental glomerulosclerosis (FSGS), a histologic pattern of injury in the glomerulus, is one of the leading glomerular causes of end-stage renal disease (ESRD) worldwide. Despite extensive research, the underlying biological alterations causing FSGS remain poorly understoo...

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Detalhes bibliográficos

Principais autores:	Amir Roointan, Maryam Ghaeidamini, Parvin Yavari, Azar Naimi, Yousof Gheisari, Alieh Gholaminejad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-09-01
coleção:	BMC Nephrology
Assuntos:	Focal and segmental glomerulosclerosis Meta-analysis Transcriptome Angiogenesis Therapeutic target
Acesso em linha:	https://doi.org/10.1186/s12882-024-03734-4
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