Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit

Encephalopathies are brain dysfunctions that lead to cognitive, sensory, and motor development impairments. Recently, the identification of several mutations within the <i>N</i>-methyl-D-aspartate receptor (NMDAR) have been identified as significant in the etiology of this group of conditions. Howev...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Jake Zheng Chen, William Bret Church, Karine Bastard, Anthony P. Duff, Thomas Balle
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2023-05-01
Saila:	Molecules
Gaiak:	molecular dynamics NMDA receptor membrane protein ligand binding encephalopathies
Sarrera elektronikoa:	https://www.mdpi.com/1420-3049/28/10/4108
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!