Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure

Aim: Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite synthesized in host organisms from specific food constituents, such as choline, carnitine and betaine. During the last decade, elevated TMAO levels have been proposed as biomarkers to estimate the risk of cardiometabolic disea...

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Автори:	Melita Videja, Reinis Vilskersts, Stanislava Korzh, Helena Cirule, Eduards Sevostjanovs, Maija Dambrova, Marina Makrecka-Kuka
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2021-01-01
Серія:	Frontiers in Cell and Developmental Biology
Предмети:	trimethylamine N-oxide right ventricular dysfunction monocrotaline mitochondrial function cardiovascular diseases
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fcell.2020.622741/full
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