Multimodal plasma and urinary cell-free DNA profiling improves risk stratification in newly diagnosed prostate cancer

Abstract Prostate cancer (PCa) is a heterogeneous disease, impeding early detection and risk stratification. Liquid biopsies (LBx) enable minimally invasive tumor profiling, but circulating tumor-derived DNA (ctDNA) detection remains difficult, particularly in early-stage PCa. We developed a multimo...

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Auteurs principaux:	Anja Lisa Riediger, Samaneh Eickelschulte, Florian Janke, Daniela Janscho, Olga Lazareva, Daniel Hübschmann, Stefan Duensing, Oliver Stegle, Holger Sültmann, Magdalena Görtz
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2026-03-01
Collection:	npj Precision Oncology
Accès en ligne:	https://doi.org/10.1038/s41698-026-01343-y
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