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Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy

The immune system plays pivotal roles in the occurrence and progression of cancers. As blockade of immune-checkpoint has been proven effective at improving anti-tumor immune response in multiple tumor types, the tumor immunotherapy still faces many challenges. Emerging evidence indicates lymphoid or...

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Main Authors: Liangbin Lin, Xiang Hu, Huiyuan Zhang, Hongbo Hu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
cancer immunology
tertiary lymphoid organ
non-canonical NF-κB
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01398/full
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