Clinical Manufacturing of Regulatory T Cell Products For Adoptive Cell Therapy and Strategies to Improve Therapeutic Efficacy

ABSTRACTBased on successes in preclinical animal transplant models, adoptive cell therapy (ACT) with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce the use of immunosuppressive drugs to prevent rejection. Extensive work has been done in optimizing the best...

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Autores principales:	Kassandra J. Baron, Hēth R. Turnquist
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis Group 2023-12-01
Colección:	Organogenesis
Materias:	Regulatory T cells GMP manufacturing ex vivo expansion solid organ transplant immunotherapy
Acceso en línea:	https://www.tandfonline.com/doi/10.1080/15476278.2022.2164159
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