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Comparison of NK alloreactivity prediction models based on KIR-MHC interactions in haematopoietic stem cell transplantation

The biological processes underlying NK cell alloreactivity in haematopoietic stem cell transplantation (HSCT) remain unclear. Many different models to predict NK alloreactivity through KIR and MHC genotyping exist, raising ambiguities in its utility and application for clinicians. We assessed 27 pre...

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Principais autores: Adèle Dhuyser, Thomas Remen, Michaël Pérès, Vitalina Chamberlain-Evans, Neda Nemat-Gorgani, Arnaud Campidelli, Sandra Clément, Marie Thérèse Rubio, John Trowsdale, Alice Aarnink, James Traherne
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Immunology
Fag:
KIR
MHC
HLA
alloreactivity
prediction
natural killer (NK)
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1028162/full
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