Protective effects of Lactobacillus rhamnosus GG supernatant on metabolic associated fatty liver disease through intestinal barrier restoration and regulation of the regenerating gene 3γ

ObjectiveThe regenerating gene 3γ (Reg IIIγ) protein, a key antimicrobial peptide, is essential for maintaining intestinal barrier homeostasis and host defense. Its expression is impaired in metabolic-associated fatty liver disease (MAFLD), particularly under high-fat diet (HFD) conditions, contribu...

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Главные авторы:	Si-Pu Wang, Ling Ba, Xin-Rui Lv, Ya-Xin Qi, Xu Wang, Jie Zhang, Xin Xu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-09-01
Серии:	Frontiers in Microbiology
Предметы:	antimicrobial peptide intestinal barrier Lactobacillus rhamnosus GG MAFLD Reg IIIγ
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1580171/full
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