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Decorin (DCN) Downregulation Activates Breast Stromal Fibroblasts and Promotes Their Pro-Carcinogenic Effects through the IL-6/STAT3/AUF1 Signaling

Decorin (DCN), a member of the small leucine-rich proteoglycan gene family, is secreted from stromal fibroblasts with non-cell-autonomous anti-breast-cancer effects. Therefore, in the present study, we sought to elucidate the function of decorin in breast stromal fibroblasts (BSFs). We first showed...

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Autori principali: Wafaa A. Aljagthmi, Manal A. Alasmari, Maha H. Daghestani, Layla A. Al-Kharashi, Falah H. Al-Mohanna, Abdelilah Aboussekhra
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-04-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/13/8/680
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