The visualizable and marker-free gene editing platform mediated by CRISPR/Cas9 in Coleophoma empetri

Abstract Micafungin, an echinocandin antifungal agent, has been extensively utilized for the treatment of invasive fungal infections. It is semi-synthesized from the lipohexapeptide FR901379, a natural product from the filamentous fungus Coleophoma empetri. The genetic manipulation of C. empetri has...

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Principais autores:	Li Xie, Ping Men, Yu Zhou, Jiang Li, Xuan Zhang, Min Wang, Xuenian Huang, Xuefeng Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-02-01
Colecção:	Applied Microbiology and Biotechnology
Assuntos:	Industrial filamentous fungi Micafungin Visualizable neutral sites CRISPR/Cas9 Marker-free screening
Acesso em linha:	https://doi.org/10.1007/s00253-026-13762-9
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