Effects of Astragaloside IV Against the TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Peritoneal Mesothelial Cells by Promoting Smad 7 Expression

Background/Aims: To investigate the effect of Astragaloside IV (AS-IV) on the regulation of the TGF-β1/Smad signaling pathway in peritoneal mesothelial cells with an epithelial-to-mesenchymal transition (EMT). Methods: EMT of human peritoneal mesothelial cells (HMrSV5) was induced using 2 ng/ml TGF-...

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Autores principales:	Lu Zhang, Zhenghong Li, Weiming He, Lingdong Xu, Jing Wang, Jun Shi, Meixiao Sheng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Colección:	Cellular Physiology and Biochemistry
Materias:	Astragaloside IV TGF-β1 Smad7 EMT Mesothelial cells Peritoneal dialysis (PD) Peritoneal fibrosis (PF)
Acceso en línea:	http://www.karger.com/Article/FullText/430332
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