Co-existence of EGFR T790M-acquired lung adenocarcinoma and transformation into small-cell carcinoma in different organs after osimertinib treatment. A case report

We report a rare case of a 59-year-old man with EGFR-mutated lung adenocarcinoma who developed osimertinib resistance, with coexisting T790M-positive adenocarcinoma and T790M-negative small-cell carcinoma in different organs. After treatment with gefitinib, chemotherapy, osimertinib, and subsequent...

Полное описание

Библиографические подробности

Главные авторы:	Masahide Takeda, Mariko Asano, Sho Sakamoto, Yuka Izumiya, Yuji Okuda, Kazuhiro Sato, Katsutoshi Nakayama
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-09-01
Серии:	Current Problems in Cancer: Case Reports
Предметы:	Lung adenocarcinoma transformation into small-cell carcinoma osimertinib
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2666621925000286
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!