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Stabilization of Self-Pressurized Gelatin Capsules for Oral Delivery of Biologics

<b>Background/Objectives:</b> Oral delivery of biologics offers advantages for patient access and adherence compared to injection, but suffers from low bioavailability due to mucosal barriers and drug degradation in the gastrointestinal tract. We previously developed an oral self-pressurized aerosol...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Amy J. Wood-Yang, Joshua I. Palacios, Abishek Sankaranarayanan, Mark R. Prausnitz
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-09-01
Schriftenreihe:Pharmaceutics
Schlagworte:
oral delivery
biologic drug
effervescence
self-pressurized capsule
high-velocity aerosol
hard gelatin capsule
Online-Zugang:https://www.mdpi.com/1999-4923/17/9/1156
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