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Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

Human African trypanosomiasis is caused by infection with parasites of the Trypanosoma brucei species complex, and threatens over 70 million people in sub-Saharan Africa. Development of new drugs is hampered by the limitations of current rodent models, particularly for stage II infections, which occ...

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Principais autores: Alex P McLatchie, Hollie Burrell-Saward, Elmarie Myburgh, Michael D Lewis, Theresa H Ward, Jeremy C Mottram, Simon L Croft, John M Kelly, Martin C Taylor
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2013-11-01
叢編:PLoS Neglected Tropical Diseases
在線閱讀:http://europepmc.org/articles/PMC3836995?pdf=render
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