Synthesis and in Vitro Antiproliferative Evaluation of Some B-norcholesteryl Benzimidazole and Benzothiazole Derivatives

Taking orostanal (a compound from a Japanese marine sponge, Stelletta hiwasaensis) as a lead compound, some novel B-norcholesteryl benzimidazole and benzothiazole derivatives were synthesized. The antiproliferative activity of the compounds against human cervical carcinoma (HeLa), human lung carcino...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jianguo Cui, Binbin Qi, Chunfang Gan, Zhipin Liu, Hu Huang, Qifu Lin, Dandan Zhao, Yanmin Huang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2015-04-01
Schriftenreihe:	Marine Drugs
Schlagworte:	cholesterol B-norcholesteryl benzimidazoles B-norcholesteryl benzothiazoles antiproliferative activity apoptosis
Online-Zugang:	http://www.mdpi.com/1660-3397/13/4/2488
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!