Chicken telomerase reverse transcriptase promotes the tumorigenicity of avian leukosis virus subgroup J by regulating the Wnt/β-catenin signaling pathway

Abstract This research aimed to analyze the regulatory effect of chicken telomerase reverse transcriptase (chTERT) on the Wnt/β-catenin signaling pathway and its effect on the tumorigenicity of avian leukosis virus subgroup J (ALV-J) through in vivo experiments. The chTERT eukaryotic expression plas...

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Hauptverfasser:	Yong Xiang, Canxin Liang, Qingbo Li, Qinxi Chen, Yang Zhou, Xiaoxue Zheng, Di Zhou, Zepeng Wang, Guyao Wang, Weisheng Cao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2022-12-01
Schriftenreihe:	Veterinary Research
Schlagworte:	Avian leukosis virus subgroup J chicken telomerase reverse transcriptase Wnt/β-catenin signaling pathway tumorigenicity in vivo
Online-Zugang:	https://doi.org/10.1186/s13567-022-01120-2
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