Conformational Selection and Induced Fit: The Behavior of Two Homologous Proteases

Abstract Protein‐ligand interactions are crucial for many cellular processes, with details of the binding mechanism being discussed as essential for biological functions. Interestingly, protein binding often involves conformational changes between two or more states, whereby different binding mechan...

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Autores principales:	Hannah Maus, Gerald Hinze, Stefan J. Hammerschmidt, Prof. Dr. Tanja Schirmeister, Prof. Dr. Thomas Basché
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley-VCH 2023-11-01
Colección:	ChemistryEurope
Materias:	binding mechanism of competitive inhibitors flaviviral proteases molecular dynamics protein folding smFRET
Acceso en línea:	https://doi.org/10.1002/ceur.202300060
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