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Mucin-Grafted Polyethylene Glycol Microparticles Enable Oral Insulin Delivery for Improving Diabetic Treatment

In this study, different ratios of mucin-grafted polyethylene-glycol-based microparticles were prepared and evaluated both in vitro and in vivo as carriers for the oral delivery of insulin. Characterization measurements showed that the insulin-loaded microparticles display irregular porosity and sha...

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Principais autores: Momoh A. Mumuni, Ugwu E. Calister, Nafiu Aminu, Kenechukwu C. Franklin, Adedokun Musiliu Oluseun, Mohammed Usman, Barikisu Abdulmumuni, Oyeniyi Y. James, Kenneth C. Ofokansi, Attama A. Anthony, Emmanuel C. Ibezim, David Díaz Díaz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-04-01
Serier:Applied Sciences
Fag:
insulin
mucin
polyethylene glycol
microparticles
toxicology
Online adgang:https://www.mdpi.com/2076-3417/10/8/2649
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