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Immunomodulatory effect of betulin and its derivatives on IL-6 expression in colorectal cancer cell lines and molecular docking insights

PurposeThis study investigated the immunomodulatory and therapeutic potential of betulin and its derivatives (EB5 and ECH147) in colorectal cancer (CRC), focusing on their effects on IL-6 expression at the molecular level and their possible application as diagnostic and therapeutic tools.MethodsHuma...

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Principais autores: Marcel Madej, Adrianna Halama, Elwira Chrobak, Ewa Bębenek, Joanna Magdalena Gola
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Molecular Biosciences
Fag:
colorectal cancer
IL-6
betulin
derivatives
mRNA
protein
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1704804/full
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