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Evaluating and improving health equity and fairness of polygenic scores

Summary: Polygenic scores (PGSs) are quantitative metrics for predicting phenotypic values, such as human height or disease status. Some PGS methods require only summary statistics of a relevant genome-wide association study (GWAS) for their score. One such method is Lassosum, which inherits the mod...

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Главные авторы: Tianyu Zhang, Geyu Zhou, Lambertus Klei, Peng Liu, Alexandra Chouldechova, Hongyu Zhao, Kathryn Roeder, Max G’Sell, Bernie Devlin
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2024-04-01
Серии:HGG Advances
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2666247724000198
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