Preparation of a Key Intermediate for the Angiotensin II Antagonist Losartan via Vilsmeier Chloroformylation
A novel preparation of 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde, a key intermediate for the synthesis of the angiotensin II antagonist Losartan potassium, via Vilsmeier chloroformylation of imidazolinone is described.
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| Format: | Artigo |
| Sprache: | Alemão |
| Veröffentlicht: |
Swiss Chemical Society
1997-06-01
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| Schriftenreihe: | CHIMIA |
| Online-Zugang: | https://www.chimia.ch/chimia/article/view/2849 |
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