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Male guanine-rich RNA sequence binding factor 1 knockout mice (Grsf1 −/− ) gain less body weight during adolescence and adulthood

Abstract The guanine-rich RNA sequence binding factor 1 (GRSF1) is an RNA-binding protein of the heterogenous nuclear ribonucleoprotein H/F (hnRNP H/F) family that binds to guanine-rich RNA sequences forming G-quadruplex structures. In mice and humans there are single copy GRSF1 genes, but multiple...

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Principais autores: Bernhard Dumoulin, Dagmar Heydeck, Desiree Jähn, Moritz Lassé, Sajad Sofi, Christoph Ufer, Hartmut Kuhn
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-12-01
Serier:Cell & Bioscience
Fag:
Gene expression regulation
Lipoxygenase
RNA binding proteins
Redox homeostasis
Embryogenesis
Hematopoiesis
Online adgang:https://doi.org/10.1186/s13578-022-00922-3
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