TLR3-overexpressing umbilical cord mesenchymal stromal cells suppress immune responses to attenuate high-risk corneal transplantation rejection

Abstract Background The success rates of high-risk corneal transplantation are significantly hindered by immunological rejection. Umbilical cord mesenchymal stem cells (UC-MSCs) have emerged as a potential solution to improve graft outcomes. Toll-like receptors (TLRs) play pivotal roles in the immun...

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Үндсэн зохиолчид:	Yaqi Cheng, Huaxin Chen, Simin Gu, Weihua Li, Huan Yu, Jianqiang Zhang, Huini Zhang, Jiayi Lin, Haocheng Zhu, Youyu Liu, Wenqiong Li, Ting Fu, Haoyu Zeng, Tao Wang, Shiqi Ling
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-07-01
Цуврал:	Stem Cell Research & Therapy
Нөхцлүүд:	Mesenchymal stromal cells Corneal transplantation rejection TLR3 Immune
Онлайн хандалт:	https://doi.org/10.1186/s13287-025-04510-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!