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Time Course of Hemodynamic Responses to Different Doses of Lipopolysaccharide in Unanesthetized Male Rats

Lipopolysaccharide (LPS) administration is a well-known method to induce systemic inflammation widely used for investigating new therapeutic strategies for sepsis treatment, which is characterized by clinical manifestations such as tachycardia and hypotension. However, there are different doses of L...

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Principais autores: Fernanda Brognara, Jaci Airton Castania, Daniel Penteado Martins Dias, Alexandre Kanashiro, Helio Cesar Salgado
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-06-01
coleção:Frontiers in Physiology
Assuntos:
lipopolysaccharide
arterial pressure
heart rate
heart rate variability
baroreflex sensitivity
unanesthetized rats
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphys.2019.00771/full
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