Generation and Genetic Stability of a PolX and 5′ MGF-Deficient African Swine Fever Virus Mutant for Vaccine Development

The African swine fever virus (ASFV) causes fatal disease in pigs and is currently spreading globally. Commercially safe vaccines are urgently required. Aiming to generate a novel live attenuated vaccine (LAV), a recombinant ASFV was generated by deleting the viral O174L (PolX) gene. However, during...

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Egile Nagusiak:	Daniel Pérez-Núñez, Daniel W. Madden, Gonzalo Vigara-Astillero, David A. Meekins, Chester D. McDowell, Bianca Libanori-Artiaga, Raquel García-Belmonte, Dashzeveg Bold, Jessie D. Trujillo, Konner Cool, Taeyong Kwon, Velmurugan Balaraman, Igor Morozov, Natasha N. Gaudreault, Yolanda Revilla, Juergen A. Richt
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2024-09-01
Saila:	Vaccines
Gaiak:	ASFV vaccine Arm/07/CBM/c2 PolX gene MGF genes NGS
Sarrera elektronikoa:	https://www.mdpi.com/2076-393X/12/10/1125
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