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A role for PaxB in regulating blebbing: experimental insights and theoretical perspectives from Dictyostelium discoideum

Abstract Eukaryotic cells migrate using pressure-driven blebs or actin polymerization driven pseudopods, with cells preferring to bleb in compressed environments where high protrusion forces are required for movement. In mammals, paxillin is a focal adhesion protein that acts as a scaffold, linking...

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Autori principali: Zully Santiago, Brian Wey, Sobana Handi Dinuka Sewwandi de Silva, Jessica Reznik, Lamina Siby, Emmanuel Asante-Asamani, Derrick Brazil
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-04-01
Serie:BMC Molecular and Cell Biology
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Accesso online:https://doi.org/10.1186/s12860-026-00584-w
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