The Significance of Angiopoietin Valency in Vascular Health and Disease

The Angiopoietin–Tie2 pathway is a key regulator of postnatal vascular maintenance and remodeling, regulating vascular barrier function and integrity. While the opposing roles of the ligands Angiopoietin-1 (Ang 1) and Angiopoietin-2 (Ang 2) have been recognized for decades, the structural mechanism...

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Autors principals:	Yan Ting Zhao, Devon D. Ehnes, Julie Mathieu, Hannele Ruohola-Baker
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-04-01
Col·lecció:	Cells
Matèries:	protein design angiogenesis Tie2 angiopoietins blood vessel
Accés en línia:	https://www.mdpi.com/2073-4409/15/9/820
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