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Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Abstract Background Severe neonatal hyperbilirubinemia could lead to kernicterus and neonatal death. This study aimed to analyze the association between single nucleotide polymorphisms in genes involved in bilirubin metabolism and the incidence of severe hyperbilirubinemia. Methods A total of 144 ne...

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Principais autores: Juan Fan, Hua-Yun He, Huan-Huan Li, Pi-Liu Wu, Lei Tang, Bo-Yin Deng, Wen-Hui Dong, Jian-Hui Wang
格式: Artigo
語言:Inglês
出版: BMC 2024-01-01
叢編:BMC Pediatrics
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在線閱讀:https://doi.org/10.1186/s12887-024-04537-0
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