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Attenuation of acute kidney injury in a murine model of neonatal Escherichia coli sepsis

IntroductionSepsis is a risk factor for acute kidney injury (AKI) in neonates, for which no effective treatment exists. The phosphodiesterase inhibitor pentoxifylline (PTX) has demonstrated renal protection from ischemia and inflammation in adult rodents. We hypothesized that addition of PTX to anti...

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Bibliografski detalji
Glavni autori: Esther M. Speer, Atilade A. Adedeji, Joyce Lin, Alexandra Khorasanchi, Asma Rasheed, Maya Bhat, Kelly Mackenzie, Randolph Hennigar, Kimberly J. Reidy, Robert P. Woroniecki
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-02-01
Serija:Frontiers in Cellular and Infection Microbiology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1507914/full
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