Self‐Boosting Programmable Release of Multiple Therapeutic Agents by Activatable Heterodimeric Prodrug‐Enzyme Assembly for Antitumor Therapy

Abstract Endogenous stimuli‐responsive prodrugs, due to their disease lesion specificity and reduced systemic toxicity, have been widely explored for antitumor therapy. However, reactive oxygen species (ROS) as classical endogenous stimuli in the tumor microenvironment (TME) are not enough to achiev...

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Detalhes bibliográficos

Principais autores:	Shanshan Jiang, Bhaskar Gurram, Junfei Zhu, Shan Lei, Yifan Zhang, Ting He, Oya Tagit, Hui Fang, Peng Huang, Jing Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-01-01
coleção:	Advanced Science
Assuntos:	antitumor therapy glucose oxidase heterodimeric prodrug reactive oxygen species self‐boosted programmable release
Acesso em linha:	https://doi.org/10.1002/advs.202409960
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