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Bystander effect of SARS-CoV-2 spike protein on human monocytic THP-1 cell activation and initiation of prothrombogenic stimulus representing severe COVID-19

Abstract Background Hypercoagulable state and thromboembolic complications are potential life-threatening events in COVID-19 patients. Our previous studies demonstrated that SARS-CoV-2 infection as well as viral spike protein expressed epithelial cells exhibit senescence with the release of inflamma...

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Hlavní autoři: Tapas Patra, Ranjit Ray
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2022-12-01
Edice:Journal of Inflammation
Témata:
COVID-19
Inflammation
Monocyte
Complement
Platelet
Cytokine
On-line přístup:https://doi.org/10.1186/s12950-022-00325-8
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