Pre-Vascularized 3-Dimensional Skin Substitutes Promote Angiogenesis and Tissue Repair in a Murine Model of Refractory Skin Ulcers

Restoring blood flow is crucial for treating refractory ulcers. Despite advancements in various biomaterials, none incorporating pre-formed blood vessels have been commercialized. To address this, we developed a pre-vascularized three-dimensional (3D) skin substitute (PV-3D skin) designed to enhance...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shota Tojo, Hiromi Miyazaki, Takami Saiki, Yasuyuki Tsunoi, Shingo Nakamura, Ryuichi Azuma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-11-01
Schriftenreihe:	Journal of Functional Biomaterials
Schlagworte:	angiogenesis regional blood flow skin substitutes skin ulcer wound healing
Online-Zugang:	https://www.mdpi.com/2079-4983/16/11/409
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