CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity

Abstract The interaction between glioblastoma cells and glioblastoma-associated macrophages (GAMs) influences the immunosuppressive tumor microenvironment, leading to ineffective immunotherapies. We hypothesized that disrupting the communication between tumors and macrophages would enhance the effic...

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Auteurs principaux:	Chan-Chuan Liu, Wen-Bin Yang, Chia-Hung Chien, Cheng-Lin Wu, Jian-Ying Chuang, Pin-Yuan Chen, Jui-Mei Chu, Siao Muk Cheng, Li-Ying Qiu, Yung-Chieh Chang, Daw-Yang Hwang, Chih-Yuan Huang, Jung-Shun Lee, Kwang-Yu Chang
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2024-06-01
Collection:	Cell Death and Disease
Accès en ligne:	https://doi.org/10.1038/s41419-024-06784-6
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