An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil’s Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer

Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations. Thus, the anticancer effect of 5-fluorouracil (5-FU) and the sulforapha...

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Hauptverfasser:	Małgorzata Milczarek, Tomasz Cierpiał, Piotr Kiełbasiński, Milena Małecka-Giełdowska, Marta Świtalska, Joanna Wietrzyk, Maciej Mazur, Katarzyna Wiktorska
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-08-01
Schriftenreihe:	Molecules
Schlagworte:	antimetabolites isoselenocyanate 5-fluorouracil sulforaphane anticancer effect
Online-Zugang:	https://www.mdpi.com/1420-3049/28/15/5808
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