Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives

A small library of highly functionalized phenylaminopyrazoles, bearing different substituents at position 1, 3, and 4 of the pyrazole ring, was prepared by the one-pot condensation of active methylene reagents, phenylisothiocyanate, and substituted hydrazine (namely, methyl- and benzyl-hydrazine). T...

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Principais autores:	Matteo Lusardi, Aldo Profumo, Chiara Rotolo, Erika Iervasi, Camillo Rosano, Andrea Spallarossa, Marco Ponassi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-09-01
coleção:	Molecules
Assuntos:	tetra-substituted pyrazoles mass-spectrometry antiproliferative activity computational simulations
Acesso em linha:	https://www.mdpi.com/1420-3049/27/18/5814
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